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Evaluation of Assays for Antibody to Hepatitis E Virus by a Serum Panel

table  1.   Characteristics of 12 Tests to Detect Antibody to HEV Evaluated by the Serum Panel

Laboratory Test Format Target HEV Protein Expression


ORF(s) System HEV Strain

1 1 EIA Recombinant 2 Insect cells Pakistan
2 2 EIA Recombinant 2 Insect cells Burma
3 3 Western
blot
Recombinant 2 Insect cells Burma
4 4 Western
blot
Recombinant 2, 3 E. coli China
2 5 EIA Recombinant 2 E. coli Burma
5 6 EIA Recombinant 2, 3 E. coli Burma, Mexico
6 7 EIA Recombinant* 2, 3 E. coli Burma, Mexico
7 8 EIA Recombinant 2, 3 E. coli Burma, Mexico
8 9 EIA Synthetic peptides 3   Burma
3 10 EIA Synthetic peptides 2   Burma
9 11 EIA Synthetic peptides 3   Burma, Mexico
10 12 EIA Synthetic peptides 2, 3   Burma, Mexico

* Artificial mosaic protein consisting of a series of short linear antigenic epitopes.

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