Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease.
| table 1 Impact scores and factor loadings of the items from the item reduction step |
|
CLDQ items
|
Proportion
with problem
|
Importance
|
Impact
|
Factor
loadings
|
| Factor 1 |
|
|
|
|
| Decreased strength |
0.69 |
3.95 |
2.73 |
0.69 |
| Fatigue |
0.80 |
3.88 |
3.10 |
0.82 |
| Decreased level of energy |
0.81 |
4.04 |
3.27 |
0.79 |
| Lack of energy |
0.59 |
4.24 |
2.50 |
0.75 |
| Feeling weak |
0.63 |
3.88 |
2.44 |
0.83 |
| Feeling worn out |
0.70 |
3.89 |
2.72 |
0.79 |
| Feeling sleepy during the day |
0.80 |
3.55 |
2.84 |
0.53 |
| Tired in the morning when you wake up |
0.59 |
4.03 |
2.38 |
0.57 |
| Tired in the afternoon |
0.77 |
3.37 |
2.59 |
0.58 |
| Drowsiness |
0.63 |
3.55 |
2.24 |
0.61 |
| Problem carrying heavy objects |
0.55 |
3.49 |
1.92 |
0.55 |
| Anxiety |
0.69 |
3.73 |
2.57 |
0.54 |
| Factor 2 |
| Feeling depressed |
0.56 |
4.00 |
2.24 |
0.51 |
| Irritability |
0.55 |
4.03 |
2.22 |
0.48 |
| Mood swings |
0.52 |
4.09 |
2.13 |
0.51 |
| Difficulty sleeping at night |
0.61 |
3.77 |
2.30 |
0.71 |
| Unable to fall asleep at night |
0.58 |
3.73 |
2.16 |
0.69 |
| The need to get up at night to urinate |
0.63 |
2.98 |
1.88 |
0.40 |
| Not feeling rested in the morning |
0.67 |
3.84 |
2.57 |
0.61 |
| Factor 3 |
| Worried about the impact your disease has on your family |
0.64 |
3.90 |
2.50 |
0.74 |
| Worried your symptoms will develop into a major problem |
0.73 |
4.02 |
2.93 |
0.79 |
| Worried never feeling any better |
0.52 |
4.36 |
2.27 |
0.60 |
| Worried condition getting worse |
0.83 |
4.08 |
3.39 |
0.81 |
| Factor 4 |
|
|
|
| Feeling bloated |
0.66 |
3.48 |
2.30 |
0.80 |
| Abdominal discomfort |
0.55 |
3.43 |
1.89 |
0.66 |
| Abdominal bloating |
0.58 |
3.81 |
2.21 |
0.83 |
| Muscle cramps at night |
0.56 |
3.58 |
2.00 |
0.47 |
| Factor 5 |
| Trouble lifting heavy objects |
0.53 |
3.59 |
1.90 |
0.51 |
| Change in eating habits |
0.56 |
3.44 |
1.93 |
0.76 |
| Not able to eat as much as before |
0.56 |
2.81 |
1.57 |
0.58 |
| Napping during the day |
0.61 |
3.23 |
1.97 |
0.56 |
| Factor 6 |
| Shortness of breath |
0.53 |
3.88 |
2.06 |
0.49 |
| Dry mouth |
0.61 |
3.33 |
2.03 |
0.52 |
| Worried about the availability of a liver if you need a transplant |
0.55 |
4.60 |
2.53 |
0.64 |
| Itching |
0.53 |
3.24 |
1.82 |
0.40 |
|
| Proportion of variance explained: factor 1, 0.224; factor 2, 0.122; factor 3, 0.110; factor 4, 0.099; factor 5, 0.098; factor 6, 0.056. |
|
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