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Boceprevir and HIV Drug Can Interact Dangerously

May 1, 2012

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Of concern to those co-infected with Hepatitis C and HIV, the FDA has confirmed that the Hep C drug, boceprevir, interferes with the HIV drug, ritonavir.

FDA: Don’t Mix New HCV Drug with HIV Drugs

By Michael Smith, North American Correspondent, MedPage Today

Published: April 26, 2012

The FDA has issued a warning against using boceprevir (Victrelis) and anti-HIV drugs that contain the protease inhibitor ritonavir (Norvir) because of possibly dangerous drug interactions.

But the agency cautioned that patients already taking boceprevir and one of the HIV regimens containing ritonavir should not stop their medications without consulting their doctors.

Physicians with patients taking boceprevir and any HIV regimen containing ritonavir should monitor them carefully to ensure that:

  • Hepatitis C treatment response – defined as no virus detected in the blood – continues.
  • Hepatitis C or HIV virologic rebound — defined as either virus detected in the blood again after previously being undetectable — does not occur.

Continue reading this entire article:
http://www.medpagetoday.com/InfectiousDisease/Hepatitis/32377

Posted by The Editors at Hepatitis Central on May 1, 2012

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