Boceprevir and HIV Drug Can Interact Dangerously
May 1, 2012
Of concern to those co-infected with Hepatitis C and HIV, the FDA has confirmed that the Hep C drug, boceprevir, interferes with the HIV drug, ritonavir.
FDA: Don’t Mix New HCV Drug with HIV Drugs
By Michael Smith, North American Correspondent, MedPage Today
Published: April 26, 2012
The FDA has issued a warning against using boceprevir (Victrelis) and anti-HIV drugs that contain the protease inhibitor ritonavir (Norvir) because of possibly dangerous drug interactions.
But the agency cautioned that patients already taking boceprevir and one of the HIV regimens containing ritonavir should not stop their medications without consulting their doctors.
Physicians with patients taking boceprevir and any HIV regimen containing ritonavir should monitor them carefully to ensure that:
- Hepatitis C treatment response – defined as no virus detected in the blood – continues.
- Hepatitis C or HIV virologic rebound — defined as either virus detected in the blood again after previously being undetectable — does not occur.
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