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How to Slow Down Liver Fibrosis

February 10, 2015

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Discover two ways to slow the advancement of liver fibrosis in patients with HCV.
How to Slow Down Liver Fibrosis

Strategies for Slowing the Progression of Liver Fibrosis in Hepatitis C

By Michael R. Page, PharmD, RPh

February 06, 2015

In 2 recent studies, statins and aspirin have been associated with lower rates of progression of liver fibrosis in patients with hepatitis C. Strategies for slowing the rate of progression of liver fibrosis are important for these reasons: (1) the high cost of treatment for hepatitis C; and (2) updated guidelines that recommend prioritizing treatment to sicker patients and postponing treatment in other groups.1-4

Statins
In animal models, statins have been shown to slow the progression of hepatic fibrosis, but this finding has only recently been evaluated in humans. Using data from the HALT-C trial, researchers Simon et al examined the relationship between statin use and changes in liver fibrosis scores.3

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http://www.hcplive.com/publications/targeted-therapies-hepatitis-c/2014/October2014/Strategies-for-Slowing-the-Progression-of-Liver-Fibrosis-in-Hepatitis-C-

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