Repurposing Allergy Meds to Treat Hep C
New HCV Drugs
Because of the great medical demand for better options, the standard of care for Hepatitis C has been a major focus of the pharmaceutical industry, and it has steadily been upgraded. Over the past several years, treatment protocols for this virus have boosted the Hepatitis C treatment success rate to the 90th percentile. The medications leading the way are now:
- Olysio (simeprevir) – FDA approved November 2013.
- Sovaldi (sofosbuvir) – FDA approved December 2013.
- Harvoni (ledipasvir and sofosbuvir) – FDA approved October 2014.
- Viekira Pak (ombitasvir, paritaprevir, and ritonavir; dasabuvir) – FDA approved December 2014.
Besides boasting a much higher ‘cure’ rate, these amazing drugs do so with fewer side effects and in about half the length of time than pegylated interferon and ribavirin.
However, only those with the most money, the best insurance plans, or those with the most advanced form of liver disease seem to be able to afford or qualify for these treatments. This is not a surprise, considering one dose can run somewhere in the vicinity of $1,000. Treating Hepatitis C in this manner can quickly put health insurance companies out of business, with a 12-week course of Sovaldi costing approximately $84,000, and a 12-week course of Harvoni carrying an approximate price tag of $94,500.
http://hepatitisnewstoday.com/2015/04/10/antihistamine-medication-may-be-a-promising-treatment-for-hepatitis-c/, Antihistamine Medication May Be a Promising Treatment for Hepatitis C,
http://stm.sciencemag.org/content/7/282/282ra49, Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, Shanshan He, et al, Retrieved April 19, 2015, Science Translational Medicine, April 2015.
http://www.aidsinfonet.org/fact_sheets/view/680, Interferon and Ribavirin, Retrieved April 23, 2015, AIDS InfoNet, 2015.
http://www.hepatitiscentral.com/news/breaking-news-viekira-pak-approved-for-hep-c/, Breaking News: Viekira Pak Approved for Hep C, Nicole Cutler, L.Ac., Retrieved April 24, 2015, Hepatitis Central, 2015.
http://www.webmd.com/drugs/2/drug-159074/chlorcyclizine-hcl-chlophedianol-hcl-oral/details#, Chlorcyclizine Hcl-Chlophedianol Hcl, Retrieved April 19, 2015, WebMD, LLC, 2015.
http://www.webmd.com/hepatitis/news/20150408/cheap-allergy-drug-may-hold-potential-as-hepatitis-c-treatment, Allergy Drug May Have Potential Against Hep C, Randy Dotinga, Retrieved April 23, 2015, WebMD, LLC, 2015.
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