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Telaprevir's Efficacy Against Hepatitis C Trumps Standard Treatment

April 14, 2010

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Results of the PROVE3 trial found that drug regimens using telaprevir were more effective against Hepatitis C than regimens without telaprevir in both treatment naïve patients and previous treatment non-responders.

Mid-stage trial notes efficacy in investigational hepatitis C treatment

By Alaric DeArment

CORK, Ireland (Apr. 9) Patients with chronic genotype 1 hepatitis C fared better when given an investigational drug developed by Johnson & Johnson division Tibotec and Vertex Pharmaceuticals than when given the standard therapy, after they had failed previous treatments, according to results of a mid-stage trial published Thursday.

The results of the 453-patient, phase 2 “PROVE3” trial, published in the New England Journal of Medicine, found that regimens based on the drug telaprevir worked better than other drugs at keeping the virus undetectable in the bloodstream.

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