The latest research & treatment news about Hepatitis C infection, diagnosis, symptoms and treatment.

Olysio® (simeprevir)

What is the dosage for Olysio®?

According to Janssen, the manufacturer of  Olysio, one capsule is taken daily with food. However, Olysio® should only be used in combination with other antiviral medications for chronic HCV infection. There are limitations to using Olysio® including those with moderate to severe hepatic impairment or patients who had previously failed therapy with a treatment regimen that included Olysio® or other HCV protein inhibitors. For all limitations, review Olysio’s Prescribing Information.

  • Genotype 1 without cirrhosis – 12 weeks of Olysio with sofosbuvir
  • Genotype 1 with compensated cirrhosis – 24 weeks of Olysio with sofosbuvir
  • Genotype 1 or 4 without cirrhosis or with compensated cirrhosis, with or without HIV co-infection – 12 weeks Olysio with peginterferon alfa and ribavirin.

 

Last Updated: November 2016

A New Chronic Hepatitis C Treatment - Olysio (simeprevir). http://www.olysio.com/, Janssen Therapeutics. Retrieved May 8, 2015.

FDA Approved New Treatment for Hepatitis C Cure. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm376449.htm, U.S. Food and Drug Administration. Retrieved May 8, 2015.

Helpful Tips When Facing Chronic Hepatitis C. http://www.olysio.com/sites/default/files/pdf/fact-sheets.pdf, Janssen Therapeutics. Retrieved May 8, 2015.

Highlights of Prescribing Information - OLYSIO. http://www.olysio.com/shared/product/olysio/prescribing-information.pdf, Janssen Therapeutics. Retrieved May 8, 2015.