Determinants of Outcome of Compensated Hepatitis C Virus-Related Cirrhosis

table 4. Univariate and Multivariate Analyses of Prognostic Factors for Survival

Variable^§	Number of Patients	Univariate Analysis		Multivariate Analysis
Variable^§	Number of Patients	P^*	Relative Risk(95% CI)	P	Relative Risk (95% CI)

Splenomegaly No	78
Yes	25	.04	2.4 (1-6.2)	NS
Alk. Ph. 87 IU/L	83
>87 IU/L	20	.03	2.6 (1-6.4)	NS
Albumin 3.4 g/dL	89
<3.4 g/dL	14	<.0001	6.0 (2.4-15.2)	<.0001	7.8 (2.9-20.1)
Prothrombin time 63%	86
<63%	17	<.0001	5.7 (2.3-14.4)	NS
Bilirubin 1.11 mg/dL	77
>1.11 mg/dL	26	.02	2.7 (1.1-6.8)	NS
Platelets 102 × 10⁹/L	79
<102 × 10⁹/L	24	.03	2.7 (1.1-6.8)	NS
Child-Pugh score A	94
B	9	<.0001	8.6 (2.5-30.3)	NS
IFN Yes	59
No	44	<.0001	6.0 (2.2-16.3)	.0002	7.6 (2.6-22)

Abbreviations: NS, not significant; CI, confidence interval; Alk. Ph., alkaline phosphatase. ^* P values were obtained by using the log-rank test. P values were obtained by using Cox regression analysis. Relative risks were calculated by comparing classes with Cox regression analysis. ^§ For multivariate analysis, variables are shown in the order of entry into the model.