Hep C Trial of Gilead-Bristol Combo Had 100% Success for Genotype 1
April 24, 2012
Treatment naïve patients with Hepatitis C genotype 1 boasted a 100 percent success rate when given Gilead’s GS-7977 and Bristol-Myers Squibb’s daclatasvir.
Gilead, Bristol hepatitis C drugs show promise in clinical trial
Published April 19, 2012
A combination of experimental hepatitis C drugs from Gilead Sciences Inc and Bristol-Myers Squibb Co showed impressive results in new clinical trial data released on Thursday, helping fuel an 11 percent rise in Gilead shares.
Gilead’s GS-7977, acquired with its $11 billion purchase of Pharmasset, when combined with Bristol’s daclatasvir led to a 100 percent response rate in previously untreated patients with the most common form of hepatitis C, according to interim data from a mid-stage trial presented at a liver disease meeting in Europe.
The results were accomplished without interferon, an injected drug that causes flu-like symptoms and other side effects that often lead patients to discontinue or delay treatment, or ribavirin, an older antiviral drug that is also currently part of all treatment regimens.
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