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Hep C Quickly Fades with an Oral Investigational Drug Combo

The Editors at Hepatitis Central
November 21, 2011

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A small Japanese study shows a quick and lasting response to an interferon-free regimen of Daclatasvir and Asunaprevir.

AASLD: Oral HCV Combo Yields Rapid Response

By Michael Smith, North American Correspondent, MedPage Today

Published: November 11, 2011

Reviewed by Dori F. Zaleznik, MD; Associate Clinical Professor of Medicine, Harvard Medical School, Boston and Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner

SAN FRANCISCO — A combination of two investigational antiviral drugs with different mechanisms of action against hepatitis C virus (HCV) yielded quick and persistent responses in previous nonresponders without the use of pegylated interferon, a researcher said here.

By week eight of treatment — and at every measurement thereafter — HCV was undetectable in all nine patients who completed treatment in the phase 2b study, according to Kazuaki Chayama, MD, PhD, of Hiroshima University in Hiroshima, Japan.

Continue reading this entire article:
http://www.medpagetoday.com/MeetingCoverage/AASLD/29610

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