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Repurposing Allergy Meds to Treat Hep C

Nicole Cutler L.Ac. May 27, 2015

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New research targets an old, over-the-counter hay fever drug in hopes that everyone in need will be able to afford a safe and effective Hepatitis C treatment.
Repurposing Allergy Meds to Treat Hep C

Recently, the breakthroughs in Hepatitis C treatment have changed the outlook of this notoriously difficult to treat liver infection. The newer Hepatitis C medications are helping more people than ever eliminate the Hepatitis C virus from their bodies.

Unfortunately, the new antiviral drugs come with an extremely high price tag – excluding many people from receiving treatment. In search of affordable Hepatitis C treatment options, researchers have tested an inexpensive, over-the-counter allergy drug and found it to be a viable therapeutic candidate.

The Old Standard of Care

For over a decade, the Hepatitis C standard of care consisted of treatment with pegylated interferon and ribavirin. This drug combination was not ideal because:

  • Side Effects – Serious side effects are common and include reduced immunity, anemia, depression and flu-like symptoms.
  • Discontinuance – About 15 percent of patients on interferon and ribavirin had to stop treatment early due to the severity of their side effects.
  • Duration – Enduring this treatment was rough as it usually required six months to a year of treatment.
  • Low Success – For those able to complete interferon/ribavirin treatment, the maximum success rate only reached just 50 percent.

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http://hepatitisnewstoday.com/2015/04/10/antihistamine-medication-may-be-a-promising-treatment-for-hepatitis-c/, Antihistamine Medication May Be a Promising Treatment for Hepatitis C,

http://stm.sciencemag.org/content/7/282/282ra49, Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, Shanshan He, et al, Retrieved April 19, 2015, Science Translational Medicine, April 2015.

http://www.aidsinfonet.org/fact_sheets/view/680, Interferon and Ribavirin, Retrieved April 23, 2015, AIDS InfoNet, 2015.

http://www.hepatitiscentral.com/news/breaking-news-viekira-pak-approved-for-hep-c/, Breaking News: Viekira Pak Approved for Hep C, Nicole Cutler, L.Ac., Retrieved April 24, 2015, Hepatitis Central, 2015.

http://www.webmd.com/drugs/2/drug-159074/chlorcyclizine-hcl-chlophedianol-hcl-oral/details#, Chlorcyclizine Hcl-Chlophedianol Hcl, Retrieved April 19, 2015, WebMD, LLC, 2015.

http://www.webmd.com/hepatitis/news/20150408/cheap-allergy-drug-may-hold-potential-as-hepatitis-c-treatment, Allergy Drug May Have Potential Against Hep C, Randy Dotinga, Retrieved April 23, 2015, WebMD, LLC, 2015.

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HepatitisCentral.com provides information regarding hepatitis and liver disease. Comments are available to the community in order to discuss these topics and obtain answers to questions through community members. The Editors at HepatitisCentral.com will not be responding to questions or comments posed in article comments.

  • smiley valenti

    Yes i started with the very first meds. an got 70% better back in around in 96 i think so long ago, now i just finish my 2 time an is neg right now.