Table 5 Features Associated With Corticosteroid Responses in the Variant Syndromes

Frequency and Nature of the Variant Syndromes of Autoimmune Liver Disease

table 5. Features Associated With Corticosteroid Responses in the Variant Syndromes

Features	Corticosteroid Responses
Features	Remission (n = 11)	Treatment Failure (n = 4)	Poor Response (n = 10)

AST (reference value, 31 U/L)	699 ± 203	520 ± 309	372 ± 162
Bilirubin (reference value, 1.1 mg/dL)	4.9 ± 1.4	5.5 ± 3.1	5.7 ± 2.6
Alkaline phosphatase (reference value, 309 U/L)	276 ± 53	881 ± 339	786 ± 174
Alkaline phosphatase 2× reference value	0 (0)^*	2 (50)	5 (50)
-Globulin (reference value, 0.7-1.7 g/dL)	3.6 ± 0.2	2.9 ± 0.5	2.7 ± 0.3
-Globulin 2× reference value	6 (54)	1/3 (33)	3 (30)
Immunoglobulin G (reference value, 700-1500 mg/dL)	3134 ± 314^§	2998 ± 713	2596 ± 357
Immunoglobulin G 2× reference value	6 (54)	2 (50)	4 (40)
SMA 1:40	10 (91)	3 (75)	6 (67)
ANA 1:40	5 (45)	3 (75)	6 (60)
DR4+	5 (45)	2 (50)	4 (40)
Autoimmune score	16 ± 1	16 ± 2	16 ± 1
Aggregate scores >15	5 (45)	2 (50)	5 (50)

NOTE. Numbers in parentheses are percentages. Abbreviation: AST, serum aspartate aminotransferase level. Significantly different from those without the response at levels of *^,P = .001, P = .004, and §P = .04.