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table 2

Neurovisual Impairment: A Frequent Complication of Alpha-Interferon Treatment in Chronic Viral Hepatitis

table  2.   Neurovisual Parameters in 53 Patients (106 Eyes) Studied Before and at the End of an Interferon Course

Parameter Before Treatment End of Treatment

P100 latency of VER (msec)* 122.8 ± 10.9dagger 126.3 ± 12.9dagger
P100 amplitude (µV)* 7.00 ± 0.80Dagger 7.60 ± 6.90Dagger
Electroretinogram (µV)* 52.7 ± 5.9Dagger 53.4 ± 6.1Dagger
Visual acuity*,§ 8.8 ± 1.9# 8.4 ± 2.1#
Visual sensitivity (db)* 24.9 ± 1.2## 23.6 ± 2.4##

* Mean ± SD.
dagger P = .036.
Dagger P = NS.
§ Snellen score (in 10ths).
#P = .002 (paired eye comparisons).
##P < .001 (paired and group comparisons).

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