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Human Testing for Inovio’s Hep C Vaccine Planned in 2013

January 15, 2013

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Due to its strong T-cell response in the liver, Inovio’s therapeutic Hepatitis C vaccine will soon be tested in humans.

Hepatitis C vaccine by Inovio could be tested in humans by end of year

Jan 9, 2013

John George, Senior Reporter- Philadelphia Business Journal

Inovio Pharmaceuticals Inc. said Wednesday it plans to begin human testing of its hepatitis C DNA vaccine by the end of the year.

Officials at the Blue Bell, Pa., biopharmaceutical company said preclinical studies demonstrated its SynCon HCV vaccine can generate “robust” T-cell responses not only in the blood, but also in the liver — an organ known to suppress T-cell activity.

“The major hurdle to developing therapeutic vaccines for these ailments has been the inability to generate a functional T-cell response in the liver [to combat the hepatitis C virus],” said Dr. J. Joseph Kim, Inovio’s president and CEO.

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http://www.bizjournals.com/philadelphia/news/2013/01/09/hepatitis-c-vaccine-by-inovio-could-be.html

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