Role of Alcohol in the Progression of Liver Disease Caused By Hepatitis C

Role of Alcohol in the Progression of Liver Disease Caused By Hepatitis C Virus Infection

table 3. Summary of Breakdown of Variables According to Fibrosis Score on Liver Biopsy

Variable	Fibrosis Score
Variable	0 (n = 15)	1 (n = 119)	2 (n = 35)	3 (n = 11)	4 (cirrhosis) (n = 50)

Age (yr)	33.5	37.4	39.1	39.1	51.6^*
Male sex (%)	(31)	(75)	(77)	(78)	(68)
HCV Duration (yr)	15.6	15.7	16.2	24.0	20.1
HCV RNA titre (×10⁵copies/mL)	3.6	1.6	1.6	4.1	1.9
HCV genotype 1 (%)	(100)	(54)	(62)	(22)	(52)
Lifetime total alcohol (kg)	101	200	185	243	289
Lifetime average daily alcohol (g)	16	27	26	38	27

NOTE. All values expressed as mean except for “male sex” and “genotype 1,” which are expressed as percentages. ^* P = .0001; P = .0002.