Histopathology of the Liver in Children With Chronic Hepatitis C Viral Infection
table 2. Summary of Histopathological Findings
|
|
Histological Finding |
Number of Specimens (%) |
|
Sinusoidal lymphocytosis |
37 (74) |
Mild |
31 (62) |
Moderate |
6 (12) |
Steatosis |
25 (50) |
Mild |
22 (44) |
Moderate |
3 (6) |
Bile duct damage |
14 (28) |
Mild |
13 (26) |
Moderate |
1 (2) |
Lymphoid aggregates and/or follicles |
24 (48) |
Aggregates |
19 (38) |
Follicles |
5 (10) |
Venous endothelialitis |
20 (40) |
Mild |
19 (38) |
Moderate |
1 (2) |
Increased stainable iron stores |
11 (22) |
Reticuloendothelial (RE) only |
4 (8) |
RE and hepatocellular |
6 (12) |
RE, hepatocellular, and bile ductular |
1 (2) |
Pigmented macrophages |
5 (10) |
Portal fibrosis |
39 (78) |
Fibrous portal expansion |
13 (26) |
Portal-portal or portal-central bridging |
11 (22) |
Bridging with architectural distortion |
11 (22) |
Cirrhosis |
4 (8) |
Centrilobular pericellular fibrosis |
26 (52) |
Mild |
23 (46) |
Moderate |
3 (6) |
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