Histopathology of the Liver in Children With Chronic Hepatitis C Viral Infection
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table 2. Summary of Histopathological Findings
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| Histological Finding |
Number of Specimens (%) |
|
| Sinusoidal lymphocytosis |
37 (74) |
| Mild |
31 (62) |
| Moderate |
6 (12) |
| Steatosis |
25 (50) |
| Mild |
22 (44) |
| Moderate |
3 (6) |
| Bile duct damage |
14 (28) |
| Mild |
13 (26) |
| Moderate |
1 (2) |
| Lymphoid aggregates and/or follicles |
24 (48) |
| Aggregates |
19 (38) |
| Follicles |
5 (10) |
| Venous endothelialitis |
20 (40) |
| Mild |
19 (38) |
| Moderate |
1 (2) |
| Increased stainable iron stores |
11 (22) |
| Reticuloendothelial (RE) only |
4 (8) |
| RE and hepatocellular |
6 (12) |
| RE, hepatocellular, and bile ductular |
1 (2) |
| Pigmented macrophages |
5 (10) |
| Portal fibrosis |
39 (78) |
| Fibrous portal expansion |
13 (26) |
| Portal-portal or portal-central bridging |
11 (22) |
| Bridging with architectural distortion |
11 (22) |
| Cirrhosis |
4 (8) |
| Centrilobular pericellular fibrosis |
26 (52) |
| Mild |
23 (46) |
| Moderate |
3 (6) |
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