Prospective Study of Interferon Therapy for Compensated Cirrhotic Patients With Chronic Hepatitis C by Monitoring Serum Hepatitis C RNA
| table 1. Demographic Features of Patients |
|
| Parameters |
Treatment
|
Total |
| +16 Weeks |
+32 Weeks |
|
| Number of patients |
37 |
36 |
157 |
| Age (year old) |
53.4 ± 9.3 |
57.7 ± 10.4 |
56.0 ± 8.8 |
| Gender (male:female) |
24:13 |
22:14 |
91:66 |
| History of blood transfusion |
16 (43%) |
17 (47%) |
73 (47%) |
| Duration after blood transfusion (years) |
27.6 ± 10.6 |
30.8 ± 6.6 |
30.0 ± 8.3 |
| Biochemical parameters |
| Albumin (g/dL) |
3.9 ± 0.4 |
3.9 ± 0.4 |
4.0 ± 0.4 |
AST (IU/l) ( SD, +SD) |
90 (55-145) |
85 (42-172) |
82 (48-141) |
ALT (IU/l) ( SD, +SD) |
110 (62-194) |
99 (41-240) |
95 (48-186) |
Bilirubin (mg/dL) ( SD, +SD) |
0.79 (0.58-1.08) |
0.83 (0.56-1.21) |
0.83 (0.58-1.17) |
| Platelet count (103/mm3) |
121 ± 42 |
122 ± 46 |
116 ± 41 |
| Virus characteristics |
| HCV RNA level (copies/mL) |
106.69±1.29 |
106.44±0.95 |
106.90±1.01 |
| HCV subtype |
| 1b |
27 |
21 |
124 |
| 2a |
8 |
10 |
24 |
| 2b |
1 |
3 |
5 |
| Mixed |
1 |
1 |
2 |
| Missing |
0 |
1 |
2 |
|
| NOTE. Data are expressed as mean ± SD. Logarithmic transformation was performed on the variables of AST, ALT, and bilirubin. |
|
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