Hepatitis C, table 1, Differences in HypervariableRegion 1 Quasispecies of Hepatitis C Virus in Human Serum,Peripheral Blood Mononuclear Cells, and Liver

Differences in Hypervariable Region 1 Quasispecies of Hepatitis C Virus in Human Serum, Peripheral Blood Mononuclear Cells, and Liver

table 1. Clinical Characteristics of Patients

Patient	Age (yr)	Sex	ALT	Histology^*		AntiHCV	HCV RNA
Patient	Age (yr)	Sex	ALT	Grading	Staging	AntiHCV	Genotype	Level (log Eq/ml)

1	58	M	173	severe	3	>2.0	1b	6.5
2	47	F	50	minimal	1	>2.0	1b	7.0
3	51	F	73	severe	4	>2.0	1b	6.4
4	27	M	50	minimal	1	>2.0	1b	7.0
5	34	F	21	minimal	1	>2.0	1b	5.8
6	45	M	35	mild	1	>2.0	1b	<5.5
7	35	M	83	moderate	2	>2.0	1b	6.2
8	45	M	151	minimal	1	>2.0	1b	6.6
9	56	M	45	mild	1	>2.0	1b	6.9
10	56	F	86	severe	3	>2.0	1b	6.8
11	56	F	93	severe	3	>2.0	1b	6.9
12	40	M	128	moderate	3	>2.0	1b	6.7
13	56	M	171	moderate	2	>2.0	1b	6.0

Abbreviation: ALT, alanine transaminase. ^* Histological diagnoses were made according to recently devised criteria for grading inflammatory activity (minimal, mild, moderate, and severe) and for staging fibrosis (F1, F2, F3, and F4).21 HCV-RNA level was measured by branched DNA probe assay. Values are cut-off index.