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Compounds Found That Halt Hepatitis C Replication

January 27, 2010

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Slowing down efforts to prevent or cure Hepatitis C, this virus has an uncanny ability to mutate and become resistant to new drugs. By identifying compounds that interfere with Hepatitis C’s replication process, scientists at Stanford University have uncovered a potentially new approach for suppressing Hepatitis C that does not appear to be vulnerable to drug resistance.

Potential New Class of Drugs to Combat Hepatitis C Identified

ScienceDaily (Jan. 25, 2010) — Stanford University School of Medicine scientists have discovered a novel class of compounds that, in experiments in vitro, inhibit replication of the virus responsible for hepatitis C. If these compounds prove effective in infected humans as well, they may dramatically accelerate efforts to confront this virus’s propensity to rapidly acquire drug resistance, while possibly skirting some of the troubling side effects common among therapies in current use and in late-stage development.

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http://www.sciencedaily.com/releases/2010/01/100120143958.htm

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Pharmasset Further Refines Its Hepatitis C Polymerase Inhibitor

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