Early Hepatitis C Trial Data Shows INX-189 to Be Effective | Hepatitis Central

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Early Hepatitis C Trial Data Shows INX-189 to Be Effective

The Editors at Hepatitis Central
January 14, 2011

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Interim data from a Phase 1b trial of Inhibitex’s INX-189 demonstrates potent antiviral activity against the Hepatitis C virus.

Inhibitex Reports Positive Data From Ongoing Phase 1b Clinical Trial Of INX-189

1/9/2011

(RTTNews) – Inhibitex, Inc. (INHX: News ) reported positive preliminary interim safety and antiviral data from the first two monotherapy cohorts of its ongoing Phase 1b clinical trial of INX-189, an oral NS5b nucleotide inhibitor being developed to treat chronic infections caused by hepatitis C virus or HCV.

The company added that the trial, which is being conducted under an IND in the United States, is a double-blind, placebo-controlled, dose escalation study, administered orally once-daily for seven days, for the treatment of HCV genotype 1 treatment naïve patients. Each treatment cohort in the study is comprised of 10 patients, eight that receive INX-189 and two that receive placebo.

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