Hepatitis C, Sequential Versus Concomitant Administration of Ribavirin and Interferon Alfa-n3 in Patients With Chronic Hepatitis C Not Responding to Interferon Alone: Results of a Randomized, Controlled Trial

table 3. Results of Univariate Logistic Regression Analysis Correlating Initial Features With Long-Term Outcome of Patients in Group 2

	Nonresponse/ Relapse	P	Sustained Response

Sex (M/F)	26/3	NS	2/2
Mean age (yr)	47.2	NS	49.2
Mean ALT (IU)	151.1	NS	130.2
Source of infection
Blood transfusion	3 (11%)	.042	2 (50%)
Intravenous drug addiction	1 (3%)		1 (25%)
Sporadic	25 (86%)		1 (25%)
Viremia (genEq/mL)
>1 × 10⁶	20 (69%)		0 (0%)
		.0001
<1 × 10⁶	9 (31%)		4 (100%)
HCV genotype
1	20 (69%)		1 (25%)
2	3 (11%)	NS	2 (50%)
3	4 (14%)		1 (25%)
4	2 (6%)		0 (0%)
Histology^*
Grading	7.3 ± 4.3	NS	6.9 ± 3.8
Staging	3.8 ± 1.2	NS	3.5 ± 1.7

^* According to Ishak et al.10