Hepatitis C, table 1, A Prospective, Community-BasedEvaluation of of Liver Enzymes in Individuals With Hepatitis C After Drug Use

A Prospective, Community-Based Evaluation of Liver Enzymes in Individuals With Hepatitis C After Drug Use

table 1. Correlates of Serial ALT Values Among HCV-Infected Individuals

	Number	ALT Not Elevated^* % (n)	ALT Elevated <50% Visits % (n)	ALT Elevated 50% Visits % (n)	ALT Always Elevated % (n)	P

Gender
Male	789	34 (271)	22 (176)	23 (183)	20 (159)
Female	253	62 (157)	15 (39)	11 (28)	11 (29)	.001
Age (yr)
<41	551	37 (203)	20 (112)	23 (129)	19 (107)
41	491	46 (225)	21 (103)	17 (82)	17 (81)	.002
Alcohol Use
Yes	665	38 (252)	22 (146)	21 (138)	19 (129)
No	377	47 (176)	18 (69)	19 (73)	16 (59)	.012
Current IDU
Yes	629	44 (279)	20 (128)	21 (132)	14 (90)
No	413	36 (149)	21 (87)	19 (79)	23 (98)	.001
HIV Negative	568	41.5 (236)	20.6 (117)	19.9 (113)	18 (102)
HIV Positive
CD4 >500	94	42.5 (40)	17.0 (16)	23.4 (22)	17.0 (16)
CD4 200-499	211	37.9 (80)	21.3 (45)	21.8 (46)	19.0 (40)
CD4 0-199	159	43.4 (69)	22.6 (36)	17.0 (27)	17.0 (27)	>.10

Abbreviations: IDU, injection drug use; CD4 count expressed in cells/mL. ^* ALT values drawn at intervals 6 mo. All individuals had at least 2, but no more than 5, measurements. Alcohol drinker defined as regular alcohol intake in 6 mo before visit. Current IDU defined as use of injection drugs in 6 mo before visit.